The most common type of adenocarcinomas comprises breast, lung, prostate, colorectal, and pancreatic. Adenocarcinoma of the lung can present with a chronic dry cough, dyspnea, hemoptysis, weight loss, or as an incidental finding on routine imaging.

SCCs can appear as scaly red patches, open sores, rough, thickened or wart-like skin, or raised growths with a central depression. At times, SCCs may crust over, itch or bleed. The lesions most commonly arise in sun-exposed areas of the body. SCCs can also occur in other areas of the body, including the genitals.

the urothelial or transitional character of cells of urothelial carcinoma include the presence of longitudinal nuclear grooves that are often appreciable usually only in low-grade tumors, but are absent to only focally present in high-grade tumors.